Corona-Virus

Ioannidis vereinigt mehrere Studien über Infektionssterblichkeit

https://onlinelibrary.wiley.com/doi/epdf.../eci.13554



Infektionssterblichkeit ungefähr 0,15% im Durchschnitt.
Allerdings weist er auch auf erhebliche Differenzen zwischen verschiedenen Kontinenten/Ländern und Regionen hin!

Results: Six systematic evaluations were eligible. Each combined data from 10-338 studies (9-50 countries), because of different eligibility criteria. Two evaluations had some overt flaws in data, violations of stated eligibility criteria, and biased eligibility criteria (e.g. excluding studies with few deaths) that consistently inflated IFR estimates. Perusal of quantitative synthesis methods also exhibited several challenges and biases. Global representativeness was low with 78-100% of the evidence coming from Europe or the Americas; the two most problematic evaluations considered only 1 study from other continents. Allowing for these caveats, 4 evaluations largely agreed in their main final estimates for global spread of the pandemic and the other two evaluations would also agree after correcting overt flaws and biases.

Conclusions: All systematic evaluations of seroprevalence data converge that SARS-CoV-2 infection is widely spread globally. Acknowledging residual uncertainties, the available evidence suggests average global IFR of ~0.15% and ~1.5-2.0 billion infections by February 2021 with substantial differences in IFR and in infection spread across continents, countries, and locations.